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Synchronous ipsilateral renal cell and transitional cell carcinoma.

Chiu CH, Lee CC, Chong PY, Ling CM, Huang HW, Chiang KH, Chou AS

Department of Medical Imaging, Hualien Buddhist Tzu Chi General Hospital, Taiwan.

The coexistence of multiple and synchronous primary neoplasms in the genitourinary system has only rarely been described in the literature. We present the case of a 78-year-old man with haematuria as the initial presentation, finally proven to be transitional cell carcinoma (TCC) combined with renal cell carcinoma (RCC). Intravenous urography (IVU), CT and arterial angiography studies revealed a space-occupying nodule at the right upper renal pelvicalyces showing mild enhancement with contrast medium. Another strong contrast medium enhancing exophytic tumour was found at the lower pole of kidney; there were hypodense foci and calcified components in this lesion. A right nephroureterectomy was performed. Pathological diagnosis was a papillary TCC and a clear cell type RCC. This is a rare case of combined renal malignancies diagnosed by imaging.

Published 26 October 2006 in Br J Radiol, 79(947): e187-9.
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