Medical Physics Research Today is a free monthly online journal that collates and summarizes the latest research about Medical Physics, including details on medicine, radiotherapy, biomechanics, medical imaging.

Leukoencephalopathy induced by levamisole alone for the treatment of recurrent aphthous ulcers.

Liu HM, Hsieh WJ, Yang CC, Wu VC, Wu KD

Department of Medical Imaging, National Taiwan University Hospital, 7, Chung-Shan S. Rd., Taipei 100, Taiwan. hml@ha.mc.ntu.edu.tw

We report imaging and clinical findings of leukoencephalopathy occurring after levamisole. The lesions were hypoattenuating on CT and appeared as multifocal oval or elliptical foci in the white matter or along the subependymal veins on MRI. Most lesions resolve after prompt withdrawal of levamisole. Detailed history taking is important for diagnosing levamisole-induced leukoencephalopathy because multiple sclerosis and acute disseminated encephalomyelitis cannot be differentiated by neuroimaging findings alone.

Published 26 September 2006 in Neurology, 67(6): 1065-7.
Full-text of this article is available online (may require subscription).

© 2005-2008 Medical Physics Research Today. All Rights Reserved.