Medical Physics Research Today is a free monthly online journal that collates and summarizes the latest research about Medical Physics, including details on medicine, radiotherapy, biomechanics, medical imaging.

MR findings of intrathecal chemotherapy-related myelopathy in two cases: mimicker of subacute combined degeneration.

Lu CH, Yao M, Liu HM, Chen YF

Department of Medical Imaging, National Taiwan University Hospital, Taipei, Taiwan.

We report the findings of spinal magnetic resonance imaging (MRI) in 2 patients who had undergone intrathecal chemotherapy and presented with the subacute onset of ascending numbness and weakness. MRI revealed a symmetric hyperintensity at the posterior columns of the spinal cord from the lower cervical region down to the conus medullaris level on T2-weighted images, and no abnormal enhancement. The imaging findings are similar to those seen in subacute combined degeneration (SCD), but the serum vitamin B(12) levels were normal in these 2 cases.

Published 19 April 2007 in J Neuroimaging, 17(2): 184-7.
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